Velpanat Those who had to deal with the treatment of hepatitis C virus, know how difficult this process was with the use of interferon and ribavirin. Not only was the treatment process difficult due to strong side effects, but the effectiveness of the therapy was low. 40 ÷ 50% of healing is the maximum, which sometimes managed to be achieved. The emergence of new drugs, such as sofosbuvir, daclatasvir and ledipasvir, which, when used in the treatment of HCV, showed an efficiency of about 97%, was far from being achieved for all virus genotypes. Therefore, pharmacists continued the search, hoping to synthesize a substance that could heal any HCV genotype. And such a substance, called velpatasvir, was created by scientists at Gilead Sciences, USA. But it is not used for monotherapy, but only in combination with sofosbuvir. Therefore, Gilead for the convenience of patients immediately combined 100 mg and sofosbuvir 400 mg in one tablet of velpatasavir. This drug was called generic epclusa , it really cured all genotypes of the virus with almost the same efficiency, and in simple cases of the disease did not require a combination with other drugs. And the only drawback of this treatment was the prohibitive cost, which exceeded $ 80,000 per course for 12 weeks.